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Pharmaceutical gelatin
Pharmaceutical gelatin
Pharmaceutical gelatin
Pharmaceutical gelatin
Pharmaceutical gelatin
Pharmaceutical gelatin

Pharmaceutical gelatin

Medicinal gelatin is a high molecular weight polypeptide polymer obtained by partial hydrolysis of collagen extracted from animal skin, bones and other connective tissues. It has good biocompatibility, can be digested and absorbed by the human body, and has almost no antigenicity and high safety. At the same time, it has unique gelling properties and can undergo a reversible sol-gel transition at different temperatures, that is, it dissolves into a sol when heated and solidifies into a gel when cooled.
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  • Detailed Description
  1. Production process：Usually, the animal raw materials are pretreated to remove impurities, and then hydrolyzed by acid, alkali or enzyme methods to decompose collagen into gelatin. After that, multiple processes such as filtration, concentration, and drying are carried out to remove impurities and reduce the content of microorganisms, and finally gelatin that meets pharmaceutical standards is obtained. The production process has strict requirements on environmental and process conditions to ensure stable and safe product quality.
  2. Quality Standards：Pharmaceutical gelatin has strict quality control standards, including physical properties (such as viscosity, freezing strength, etc.), chemical properties (such as pH value, ash content, heavy metal content, etc.) and microbial limits. For example, freezing strength is an important indicator to measure the quality of gelatin. The higher the freezing strength value, the better the gel strength of the gelatin; the heavy metal content must be strictly controlled at an extremely low level to ensure the safety of medication.
  3. Application in pharmaceutical industry
    • Hard Capsules：It is the main raw material for hard capsules. The capsule shell made of it has good elasticity and toughness, which can protect the drug from being destroyed by gastric acid and cover up the bad smell of the drug. After filling the drug, it can quickly disintegrate in the gastrointestinal tract and release the drug.
    • Soft Capsules：Used to encapsulate oily drugs, liquid drugs or drug solutions, and made into soft capsules through compression or dripping process. Soft capsules have good sealing properties, can prevent drug oxidation and volatilization, and improve drug stability.
    • Tablet Binders：As a binder in tablet production, it binds drug powders together to make tablets with a certain shape and hardness, ensuring that the tablets are not easily broken during storage and transportation.
    • Microcapsule materials：It can be used as the wall material of microcapsules to encapsulate drugs into tiny capsule particles, achieve slow release of drugs, prolong drug action time, and improve drug bioavailability.
  4. Safety and precautions：Although pharmaceutical gelatin is relatively safe, we still need to pay attention to its source and the risks in the production process. For example, if the raw materials are contaminated or the production process is improper, harmful substances may be introduced. In addition, for some special groups, such as those who are allergic to animal protein, they need to be cautious when using medicines containing gelatin, as they may cause allergic reactions.
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Registration number: LuICP20018609
Registration number: LuICP20018609